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Mississippi Drug Addiction Hotlines and Text Numbers

If you or someone you love in Mississippi is struggling with drug or alcohol use, help is available. Drug and alcohol hotline numbers and text message support services offer assistance from trained professionals. Whether you need crisis support, treatment information, or just someone to talk to, these resources can connect you with the help you need.
If you or a loved one are experiencing a medical emergency, call 9-1-1 immediately.

Lifelines for Urgent Support in Mississippi

The 988 Suicide & Crisis Lifeline is available 24/7/365 for anyone experiencing emotional distress or suicidal thoughts. Free resources and support are available now when you call or text.

Crisis Text Line – Text “HOME” to 741741

The Crisis Text Line provides text support for those in crisis, 24/7/365. Trained Crisis Counselors are available around the clock to talk right now from a secure online platform.

Poison Control – 1-800-222-1222

Poison Control can provide guidance and support from a poison expert 24/7/365 via an anonymous, free helpline. If you suspect an overdose, call 911 immediately.

Addiction Helplines in Mississippi

Mississippi National Rehab Hotline – 866-210-1303

The Mississippi National Rehab Hotline is a free service that operates a24/7/365 and provides assistance to individuals facing challenges related to substance use or mental health. Dedicated specialists can provide information on treatment options, offer immediate crisis intervention, and connect you with local resources to help you or your loved one take the next steps toward recovery.

Mississippi Department of Mental Health – 1-877-210-8513

The Mississippi Department of Mental Health Helpline is available around the clock to provide information and local Mississippi resources related to a variety of mental health concerns, including addiction. Trained staff can connect you with mental health and addiction treatment resources available throughout the state.

Boys Town National Hotline – 1-800-448-3000

Boys Town National Hotline is available 24 hours a day, 7 days a week. Information, resources, and support for addiction and mental health are available when you call.

National Alliance on Mental Illness (NAMI) Helpline – 1-800-950-6264

The National Alliance on Mental Illness (NAMI) provides free support, including counseling and treatment referrals, for individuals and families affected by addiction and other mental health conditions. Help is available Monday through Friday from 10 a.m. to 10 p.m. EST.

National Drug Helpline – 1-844-289-0879

Get confidential and free help, including referrals to addiction treatment centers, from trusted addiction specialists around the clock, 24/7/365.

National Rehab Hotline – 1-866-210-1303

The National Rehab Hotline provides free resources and support from a team of specialists trained in helping people experiencing a mental health or substance use crisis. The Hotline also offers information on counseling, mental health, and treatment.

National Runaway Safeline – 1-800-RUNAWAY (786-2929)

Find support and resources for individuals experiencing homelessness, runaway youth, and families in crisis at this 24/7 helpline.

Substance Abuse and Mental Health Services Administration – 1-800-622-HELP (4357)

SAMHSA’s National Helpline provides information, support, and referrals to local resources for individuals with mental illness and substance use disorders—available 24/7/365.




FAQs About Addiction Hotlines


Take the Next Step

If you or someone you love is struggling with substance use, speaking to someone can make all the difference. Call a drug or alcohol hotline to get immediate support, learn about treatment options, and take the first step toward recovery. Prefer to explore on your own? You can also find rehabs near you using our search tool and filter by insurance provider, level of care, location, and other important factors—so you can take the next step toward recovery with confidence.